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Open Cancer Trials

INDICATION

SUMMARY

ANEMIA IN NSCLC

 

Anemia in NSCLC

Amgen 20070782 – Evaluate the long-term safety and efficacy of darbepoetin alfa administered at 500µg once-every-3-weeks in anemic subjects with advanced stage NSCLC receiving multi-cycle chemotherapy

BREAST

 

HER2/ErB2 Positive Primary Breast Cancer

 

CALGB N063D – ALTTO:  Adjuvant Lapatinib and/or Trastuzumab treatment optimisation study with HER2/ErB2 positive primary breast cancer

COLORECTAL

 

Untreated Metastatic Adenocarcinoma of the Colon or Rectum

 

CALGB S80405 – Irinotecan/5-FU/Leucovorin or Oxaliplatin/5-FU/Leucovorin with Bevacizumab, or Cetuximab, or with the combination of Bevacizumab and Cetuximab for patients with untreated metastatic adenocarcinoma of the colon or rectum

LUNG

 

Completely Resected Stage IB-IIIA NSCLC

 

Non-Small Cell Lung

 

ECOG 1505 – Adjuvant chemotherapy with or without Bevacizumab for patients with completely resected stage IB-IIIA non-small cell lung cancer

CA196-005 –Study of Carboplatin/Paclitaxel/CT-322 versus Carboplatin/Paclitaxel/Bevacizumab as first-line treatment for recurrent or advanced non-small cell lung cancer with non-squamous histology

MELANOMA

 

First-Line Therapy for Stage IV Melanoma

Eisai E7080-702 – E7080 in combination with dacarbazine versus dacarbazine alone

MULTIPLE MYELOMA

 

Relapsed Multiple Myeloma

Novartis CLBH589D2308 – Double-blind, placebo-controlled study of panobinostat in combination with bortezomib and dexamethasone

NON-HODGKIN’S LYMPHOMA

 

Rituximab-Refractory, Indolent Non-Hodgkin’s Lymphoma

Genentech GAO4753g – Bendamustine Compared with Bendamustine + study drug in patients with rituximab-refractory indolent Non-Hodgkin’s lymphoma

OVARIAN

 

Platinum-Resistant Ovarian Cancer

Endocyte EC-FV-06 – Study Drug + Doxorubicin vs. Doxorubicin + Placebo in participants with platinum-resistant ovarian cancer

PROSTATE

 

Prostate Cancer Metastatic to Bone

CALGB 90202 – zoledronic acid (Zometa) to prevent skeletal related events in prostate cancer metastatic to bone

   
Helsinn cancer study for nausea and vomiting with chemotherapy.

Other trials

Indication: Irritable Bowel Syndrome - Non-Constipation
Brief Summary: Salix RFIB3007 - Study to assess efficacy and safety of Rifaximin, in subjects with non-constipation irritable bowel syndrome
Principal Investigator: Nelson L. Ferreira, MD
Sub-Investigator: James Cremins, MD; Rashid Hanif, MD; Christine Lewis, MD
   
Indication: Irritable Bowel Syndrome - Diarrhea
Brief Summary: Measurement of bile acids and fecal fats in irritable bowel syndrome-diarrhea or functional diarrhea in patient's stools
Principal Investigator: Mary E. Money, MD
   
Indication: Chronic Constipation
Brief Summary: Linaclotide 12 weeks administered patients with chronic constipation
Principal Investigator: Nelson L. Ferreira, MD
Sub-Investigators: James Cremins, MD; Christine Lewis, MD; Juan A. Tayler, MD
   
Indication: GERD - Gastroesophageal Reflux Disease
Brief Summary: Comparing Aaphex 50 mg versus Nexium 40 mg for healing and symptomatic relief
Principal Investigator: Nelson L. Ferreira, MD
Sub-Investigator: James Cremins, MD; Christine Lewis, MD; Juan A. Tayler, MD
   
Indication: Irritable Bowel Syndrome (IBS) - Constipation
Brief Summary: Linaclotide 12 weeks administered with IBS constipation
Principal Investigator: Nelson L. Ferreira, MD
Sub-Investigator: James Cremins, MD; Christine Lewis, MD; Juan A. Tayler, MD

 

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